GRB14 anticorps

N° du produit ABIN7114783

Détail du produit anti-GRB14 anticorps

Antigène: GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRB14 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: growth factor receptor-bound protein 14

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur GRB14

Antigène: GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))

Autre désignation: GRB14 (GRB14 Produits)

Synonymes: anticorps GRB14, anticorps AI505286, anticorps growth factor receptor bound protein 14, anticorps GRB14, anticorps grb14, anticorps Grb14

Sujet: Synonyms: Background:Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor(INSR). Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.

Poids moléculaire: 61kd

ID gène: 2888

UniProt: Q14449