INSIG2 anticorps

N° du produit ABIN7115275

Cet anticorps Lapin Polyclonal détecte spécifiquement INSIG2 dans WB, ELISA, IHC et IF. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour INSIG2 anticorps (ABIN7115275)

Antigène: INSIG2 (Insulin Induced Gene 2 (INSIG2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp INSIG2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-INSIG2 anticorps

Fonction: INSIG2 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: insulin induced gene 2

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur INSIG2

Antigène: INSIG2 (Insulin Induced Gene 2 (INSIG2))

Autre désignation: INSIG2

Sujet:

Synonyms: Insulin-induced gene 2 protein (INSIG-2)|INSIG2

Background: Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins(SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Seems to regulate the ubiquitin-mediated proteasomal degradation of HMGCR.

Poids moléculaire: 30 kDa

ID gène: 51141

UniProt: Q9Y5U4

Pathways: ER-Nucleus Signaling