INSIG2 anticorps

N° du produit ABIN7115275

Détail du produit anti-INSIG2 anticorps

Antigène: INSIG2 (Insulin Induced Gene 2 (INSIG2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp INSIG2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: insulin induced gene 2

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur INSIG2

Antigène: INSIG2 (Insulin Induced Gene 2 (INSIG2))

Autre désignation: INSIG2 (INSIG2 Produits)

Synonymes: anticorps MGC82156, anticorps INSIG-2, anticorps 2900053I11Rik, anticorps C730043J18Rik, anticorps Insig-2, anticorps insulin induced gene 2, anticorps insulin induced gene 2 L homeolog, anticorps insig2, anticorps insig2.L, anticorps INSIG2, anticorps Insig2

Sujet: Synonyms: Background:Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins(SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Seems to regulate the ubiquitin-mediated proteasomal degradation of HMGCR.

Poids moléculaire: 30 kDa

ID gène: 51141

UniProt: Q9Y5U4

Pathways: ER-Nucleus Signaling