INSIG2 anticorps (AA 40-120)

N° du produit ABIN7229148

Cet anticorps Lapin Polyclonal détecte spécifiquement INSIG2 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour INSIG2 anticorps (AA 40-120) (ABIN7229148)

Antigène: INSIG2 (Insulin Induced Gene 2 (INSIG2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp INSIG2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-INSIG2 anticorps

Épitope: AA 40-120

Fonction: Rabbit Anti-INSI2 Polyclonal Antibody

Specificité: The antibody detects endogenous levels of INSI2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from part region of human INSI2 protein at AA range: 40-120

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur INSIG2

Antigène: INSIG2 (Insulin Induced Gene 2 (INSIG2))

Autre désignation: INSI2

Sujet: Insulin-induced gene 2 protein, INSIG-2INSIG2 (Insulin Induced Gene 2) is a Protein Coding gene. Among its related pathways are Metabolism and Sterol Regulatory Element-Binding Proteins (SREBP) signalling. The protein encoded by INSIG2 is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 protein and this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element binding proteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPs to the Golgi.

Poids moléculaire: 24kD

ID gène: 51141

UniProt: Q9Y5U4

Pathways: ER-Nucleus Signaling