IFIT1 anticorps

N° du produit ABIN7115381

Détail du produit anti-IFIT1 anticorps

Antigène: IFIT1 (Interferon-Induced Protein with Tetratricopeptide Repeats 1 (IFIT1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IFIT1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: interferon-induced protein with tetratricopeptide repeats 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur IFIT1

Antigène: IFIT1 (Interferon-Induced Protein with Tetratricopeptide Repeats 1 (IFIT1))

Autre désignation: IFIT1 (IFIT1 Produits)

Synonymes: anticorps C56, anticorps G10P1, anticorps IFI-56, anticorps IFI-56K, anticorps IFI56, anticorps IFIT-1, anticorps IFNAI1, anticorps ISG56, anticorps P56, anticorps RNM561, anticorps Ifi56, anticorps Garg16, anticorps DKFZp469C2331, anticorps interferon induced protein with tetratricopeptide repeats 1, anticorps interferon-induced protein with tetratricopeptide repeats 1, anticorps IFIT1, anticorps Ifit1, anticorps LOC488947, anticorps ifit1, anticorps LOC100058990, anticorps LOC100139670, anticorps LOC100475782

Sujet: Synonyms:G10P1, GARG 16, IFI 56, IFI 56K, IFI56, IFIT 1, IFIT1, IFNAI1, ISG56, RNM561 Background:Interferon-induced antiviral RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group(PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs and inhibiting expression of viral messenger RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation(cap snatching mechanism). Exhibits antiviral activity against several viruses including human papilloma and hepatitis C viruses.

Poids moléculaire: 55 kDa

ID gène: 3434

UniProt: P09914

Pathways: Hepatitis C