KLHL22 anticorps

N° du produit ABIN7115599

Détail du produit anti-KLHL22 anticorps

Antigène: KLHL22 (Kelch-Like 22 (KLHL22))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLHL22 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: kelch-like 22(Drosophila)

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur KLHL22

Antigène: KLHL22 (Kelch-Like 22 (KLHL22))

Autre désignation: KLHL22 (KLHL22 Produits)

Synonymes: anticorps 2610318I18Rik, anticorps Kelchl, anticorps KELCHL, anticorps RGD1306288, anticorps kelch-like 22, anticorps kelch like family member 22, anticorps kelch-like family member 22, anticorps Klhl22, anticorps KLHL22

Sujet: Synonyms: Background:Substrate-specific adapter of a BCR(BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for chromosome alignment and localization of PLK1 at kinetochores. The BCR(KLHL22) ubiquitin ligase complex mediates monoubiquitination of PLK1, leading to PLK1 dissociation from phosphoreceptor proteins and subsequent removal from kinetochores, allowing silencing of the spindle assembly checkpoint(SAC) and chromosome segregation. Monoubiquitination of PLK1 does not lead to PLK1 degradation.

Poids moléculaire: 72 kDa

ID gène: 84861

UniProt: Q53GT1