anticorps zgc:63897, anticorps PLEKHF1, anticorps APPD, anticorps LAPF, anticorps PHAFIN1, anticorps ZFYVE15, anticorps 1810013P09Rik, anticorps pleckstrin homology domain containing, family F (with FYVE domain) member 1, anticorps pleckstrin homology and FYVE domain containing 1, anticorps plekhf1, anticorps PLEKHF1, anticorps Plekhf1
Sujet
Synonyms:Apoptosis inducing protein, APPD, LAPF, Phafin 1, PHAFIN1, PLEKHF1, ZFYVE15 Background:May induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane(LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization(MMP) resulting in the release of PDCD8.