PLEKHF1 anticorps (AA 75-124)

N° du produit ABIN872648

Détail du produit anti-PLEKHF1 anticorps

Antigène: PLEKHF1 (Pleckstrin Homology Domain Containing, Family F (With FYVE Domain) Member 1 (PLEKHF1))

Épitope: AA 75-124

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLEKHF1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Souris, Rat

Homologie: Human,Dog,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human APPD/ Apoptosis-inducing protein

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur PLEKHF1

Antigène: PLEKHF1 (Pleckstrin Homology Domain Containing, Family F (With FYVE Domain) Member 1 (PLEKHF1))

Autre désignation: APPD (PLEKHF1 Produits)

Synonymes: anticorps zgc:63897, anticorps PLEKHF1, anticorps APPD, anticorps LAPF, anticorps PHAFIN1, anticorps ZFYVE15, anticorps 1810013P09Rik, anticorps pleckstrin homology domain containing, family F (with FYVE domain) member 1, anticorps pleckstrin homology and FYVE domain containing 1, anticorps plekhf1, anticorps PLEKHF1, anticorps Plekhf1

Sujet:

Synonyms: APPD, LAPF, PHAFIN1, ZFYVE15, Pleckstrin homology domain-containing family F member 1, PH domain-containing family F member 1, Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains, Apoptosis-inducing protein, PH and FYVE domain-containing protein 1, Phafin-1, Zinc finger FYVE domain-containing protein 15, PLEKHF1

Background: May induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8.

ID gène: 79156

UniProt: Q96S99