RNLS anticorps

N° du produit ABIN7118395

Détail du produit anti-RNLS anticorps

Antigène: RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNLS est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: chromosome 10 open reading frame 59

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:5000, IHC: 1:20-1:200, IP: 1:200-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur RNLS

Antigène: RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))

Autre désignation: RENALASE (RNLS Produits)

Synonymes: anticorps zgc:92286, anticorps C10orf59, anticorps RENALASE, anticorps 6530404N21Rik, anticorps AI452315, anticorps AW060440, anticorps RGD1309804, anticorps renalase, FAD dependent amine oxidase, anticorps renalase, FAD-dependent amine oxidase, anticorps RNLS, anticorps rnls, anticorps Rnls

Sujet: Synonyms:C10orf59, MAO C, Monoamine oxidase C, RENALASE, RNLS Background:RNLS, also named as Renalase, C10orf59 and MAO-C, belongs to the renalase family. It is probable FAD-dependent amine oxidase secreted by the kidney, which circulates in blood and modulates cardiac function and systemic blood pressure. RNLS degrades catecholamines such as dopamine, norepinephrine and epinephrine in vitro. It lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis. RNLS has physiologically relevant catecholamine-oxidizing activity.(PMID:15841207) This antibody is specific to RNLS.

Poids moléculaire: 35 kDa

ID gène: 55328

UniProt: Q5VYX0