ARHGEF4 anticorps

N° du produit ABIN7118493

Cet anticorps anti-ARHGEF4 est un anticorps Lapin Polyclonal détectant ARHGEF4 dans WB, ELISA et IHC. Adapté pour Humain et Souris.

Aperçu rapide pour ARHGEF4 anticorps (ABIN7118493)

Antigène: ARHGEF4 (rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGEF4 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-ARHGEF4 anticorps

Fonction: ARHGEF4 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: Rho guanine nucleotide exchange factor(GEF) 4

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur ARHGEF4

Antigène: ARHGEF4 (rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4))

Autre désignation: ARHGEF4

Sujet:

Synonyms: Rho guanine nucleotide exchange factor 4|APC-stimulated guanine nucleotide exchange factor 1 (Asef, Asef1)|ARHGEF4|KIAA1112

Background: Acts as guanine nucleotide exchange factor(GEF) for RHOA, RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.

Poids moléculaire: 72 kDa

ID gène: 50649

UniProt: Q9NR80

Pathways: Neurotrophin Signaling Pathway