SOS1 anticorps
Aperçu rapide pour SOS1 anticorps (ABIN7119340)
Antigène
Voir toutes SOS1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- SOS1 antibody
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Purification
- Immunogen affinity purified
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Pureté
- ≥95 % as determined by SDS-PAGE
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Immunogène
- son of sevenless homolog 1
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Isotype
- IgG
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Indications d'application
- WB: 1:500 - 1:2000, IF: 1:50 - 1:100
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze / thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- -20°C for 12 months
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Date de péremption
- 12 months
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- SOS1 (Son of Sevenless Homolog 1 (SOS1))
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Autre désignation
- SOS1
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Sujet
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Synonyms: Son of sevenless homolog 1 (SOS-1)|SOS1
Background: Promotes the exchange of Ras-bound GDP by GTP(PubMed:8493579). Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF(PubMed:17339331). Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor(GEF) activity(By similarity).
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Poids moléculaire
- 180 kDa
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ID gène
- 6654
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UniProt
- Q07889
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Pathways
- Signalisation RTK, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
Antigène
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