SOCS1 anticorps

N° du produit ABIN7119604

Cet anticorps Lapin Polyclonal détecte spécifiquement SOCS1 dans WB, ELISA, IHC et IF. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour SOCS1 anticorps (ABIN7119604)

Antigène: SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOCS1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-SOCS1 anticorps

Fonction: SOCS1 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: peptide

Immunogen: Suppressor of cytokine signaling 1

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500 - 1:2000, IHC: 1:50-1:200, IF: 1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur SOCS1

Antigène: SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))

Autre désignation: SOCS1

Sujet:

Synonyms: Suppressor of cytokine signaling 1 (SOCS-1)|JAK-binding protein (JAB)|STAT-induced STAT inhibitor 1 (SSI-1)|Tec-interacting protein 3 (TIP-3)|SOCS1|SSI1|TIP3

Background: This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.

Poids moléculaire: 24 kDa

ID gène: 8651

UniProt: O15524

Pathways: Signalistation JAK/STAT, Interferon-gamma Pathway, Signalisation TLR, Response to Growth Hormone Stimulus