TRAF3 anticorps

N° du produit ABIN7119986

L’anticorps Lapin Polyclonal anti-TRAF3 a été validé pour WB, ELISA et IHC. Il convient pour détecter TRAF3 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour TRAF3 anticorps (ABIN7119986)

Antigène: TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRAF3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-TRAF3 anticorps

Fonction: TRAF3 antibody

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: TNF receptor-associated factor 3

Isotype: IgG

Information d'application

Indications d'application: WB: 1:200 - 1:1000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur TRAF3

Antigène: TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))

Autre désignation: TRAF3

Sujet:

Synonyms: TNF receptor-associated factor 3|CD40 receptor-associated factor 1 (CRAF1)|CD40-binding protein (CD40BP)|LMP1-associated protein 1 (LAP1)|RING-type E3 ubiquitin transferase TRAF3|TRAF3|CAP-1|CRAF1|TRAFAMN

Background: The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported.

Poids moléculaire: 70 kDa

ID gène: 7187

UniProt: Q13114

Pathways: Signalisation NF-kappaB, Apoptose, Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades