TLR4 anticorps (AA 650-839)

N° du produit ABIN7120005

Cet anticorps anti-TLR4 est un anticorps Souris Monoclonal détectant TLR4 dans WB, IHC et ELISA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour TLR4 anticorps (AA 650-839) (ABIN7120005)

Antigène: TLR4 (Toll-Like Receptor 4 (TLR4))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TLR4 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 3E7

Détail du produit anti-TLR4 anticorps

Épitope: AA 650-839

Fonction: TLR4 antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 650-839aa

Immunogen: toll-like receptor 4

Isotype: IgG2b

Information d'application

Indications d'application: WB: 1:1000-1:8000, IHC: 1:50-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months

Date de péremption: 12 months

Détails sur TLR4

Antigène: TLR4 (Toll-Like Receptor 4 (TLR4))

Autre désignation: TLR4

Sujet:

Synonyms: Toll-like receptor 4|hToll|TLR4

Background: TLR4, also named as CD284, belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.

Poids moléculaire: 100 kDa

ID gène: 7099

UniProt: O00206

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins