TMEM59 anticorps

N° du produit ABIN7120234

Détail du produit anti-TMEM59 anticorps

Antigène: TMEM59 (Transmembrane Protein 59 (TMEM59))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMEM59 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: transmembrane protein 59

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur TMEM59

Antigène: TMEM59 (Transmembrane Protein 59 (TMEM59))

Autre désignation: TMEM59 (TMEM59 Produits)

Synonymes: anticorps Tmem59, anticorps C1orf8, anticorps HSPC001, anticorps 1110001M20Rik, anticorps 3110046P06Rik, anticorps AI256529, anticorps D4Ertd20e, anticorps MTDCF1, anticorps ORF18, anticorps transmembrane protein 59, anticorps tmem59, anticorps Tmem59, anticorps TMEM59

Sujet: Synonyms:C1orf8 Background:Acts as a regulator of autophagy in response to S.aureus infection by promoting activation of LC3(MAP1LC3A, MAP1LC3B or MAP1LC3C). Acts by interacting with ATG16L1, leading to promote a functional complex between LC3 and ATG16L1 and promoting LC3 lipidation and subsequent activation of autophagy. Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. Inhibits APP transport to the cell surface and further shedding.

Poids moléculaire: 41 kDa

ID gène: 9528

UniProt: Q9BXS4