WTAP anticorps

N° du produit ABIN7120845

Détail du produit anti-WTAP anticorps

Antigène: WTAP (Wilms Tumor 1 Associated Protein (WTAP))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp WTAP est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: Wilms tumor 1 associated protein

Clone: 9D4

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:1000-1:10000, IHC: 1:50-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur WTAP

Antigène: WTAP (Wilms Tumor 1 Associated Protein (WTAP))

Autre désignation: WTAP (WTAP Produits)

Synonymes: anticorps MGC75954, anticorps WTAP, anticorps RGD1563824, anticorps wu:fi29a09, anticorps zgc:66202, anticorps 2810408K05Rik, anticorps 9430038B09Rik, anticorps WT1 associated protein, anticorps Wilms tumor 1 associated protein, anticorps wilms tumor 1 associated protein, anticorps WT1 associated protein L homeolog, anticorps Wilms tumour 1-associating protein, anticorps wtap, anticorps WTAP, anticorps CpipJ_CPIJ006489, anticorps Wtap, anticorps wtap.L

Sujet: Synonyms:DKFZp686F20131, Female lethal(2)D homolog, hFL(2)D, KIAA0105, WT1 associated protein, WTAP Background:Regulatory subunit of the WMM N6-methyltransferase complex, a multiprotein complex that mediates N6-methyladenosine(m6A) methylation of some adenosine residues of some mRNAs and plays a role in the efficiency of mRNA splicing, processing and mRNA stability. Required for accumulation of METTL3 and METTL14 to nuclear speckle(PubMed:24316715, PubMed:24407421, PubMed:24981863). Acts as a mRNA splicing regulator(PubMed:12444081). Regulates G2/M cell-cycle transition by binding to the 3' UTR of CCNA2, which enhances its stability(PubMed:17088532). Impairs WT1 DNA-binding ability and inhibits expression of WT1 target genes(PubMed:17095724).

Poids moléculaire: 49 kDa

ID gène: 9589

UniProt: Q15007