GPR177/WLS anticorps

N° du produit ABIN7120857

Détail du produit anti-GPR177/WLS anticorps

Antigène: GPR177/WLS (WLS) (Wntless Homolog (WLS))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPR177/WLS est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène: G protein-coupled receptor 177

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:1000, IP: 1:500-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur GPR177/WLS

Antigène: GPR177/WLS (WLS) (Wntless Homolog (WLS))

Autre désignation: GPR177 (WLS Produits)

Synonymes: anticorps C1orf139, anticorps EVI, anticorps GPR177, anticorps MRP, anticorps mig-14, anticorps 5031439A09Rik, anticorps AI173978, anticorps AI987742, anticorps Gpr177, anticorps gpr117, anticorps gpr177, anticorps sb:cb610, anticorps wu:fb36d04, anticorps wu:fb44d10, anticorps wu:fb50c06, anticorps zgc:64091, anticorps CG6210, anticorps Dmel\\CG6210, anticorps Evi, anticorps Evi/Wls, anticorps Srt, anticorps Wls, anticorps Wls/Evi, anticorps evi, anticorps srt, anticorps wls/evi, anticorps wntless Wnt ligand secretion mediator, anticorps wntless homolog (Drosophila), anticorps wntless, anticorps WLS, anticorps Wls, anticorps wls

Sujet: Synonyms:C1orf139, EVI, G protein coupled receptor 177, GPR177, Protein wntless homolog, Sprinter, WLS, Wntless Background:GPR177, also known as Wntless (WLS) or Evi, is an evolutionarily conserved transmembrane protein necessary for Wnt protein secretion. GPR177 localizes to compartments of the secretory pathway, including the ER, Golgi apparatus, endosomes, and plasma membrane. GPR177 is overexpressed in several cancer types including glioma and gastric cancer. Several isoforms of GPR177 exist due to the alternative splicing, with predicted MW around 62 and 51 kDa, respectively. The sequence can be processed by removing the signal peptide, which generates a mature form of 45-46 kDa. In addition, slow migragrating band above 62 kDa can also be detected because GPR177 is modified by N-linked glycosylation (PMID: 20549736).

Poids moléculaire: 46-62 kDa

ID gène: 79971

UniProt: Q5T9L3

Pathways: Signalisation WNT