SARS-CoV-2 Spike anticorps

N° du produit ABIN7121593

Détail du produit anti-SARS-CoV-2 Spike anticorps

Antigène: SARS-CoV-2 Spike

Reactivité: SARS-CoV-2

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SARS-CoV-2 Spike est non-conjugé

Application: ELISA

Fonction: SARS-CoV-2 Whole Spike Protein Antibody

Specificité: Anti-SARS-CoV-2 Whole Spike antibody is directed against SARS Coronavirus 2 Spike (S) protein.

Réactivité croisée (Details): No reactivity was seen against SARS COV-2 Spike S1 subunit, SARS COV-2 Spike S1 RBD, SARS COV-2 loop, SARS COV-2 (N), MERS CoV. Cross reactivity with homologues from other sources has not been determined.

Purification: The product was purified from roller bottle culture by protein A chromatography. BLAST analysis was used to suggest reactivity with related Coronavirus proteins.

Stérilité: Sterile filtered

Immunogène: This protein A purified antibody was produced by repeated immunizations with a purified SARS-CoV-2 S protein with His-tag, derived from the transfected human HEK293 cells.

Clone: 15D9-E2-C10

Isotype: IgG

Information d'application

Indications d'application: Anti-SARS-CoV-2 Whole Spike protein antibody has been tested for use in ELISA and shows reactivity to SARS COV-2 Whole Spike and COV-2 Spike (S2) protein. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01% (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Détails sur SARS-CoV-2 Spike

Antigène: SARS-CoV-2 Spike

Abstract: SARS-CoV-2 Spike Produits

Synonymes: anticorps E2, anticorps E2 glycoprotein precursor, anticorps Surface Glycoprotein, anticorps S

Classe de substances: Viral Protein

Sujet: SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2) the virus that causes the disease COVID-19, is related to SARS-CoV, MERS-CoV, and other betacoronaviruses (HKU1, NL63, OC43 and 229E). SARS-CoV-2 is an enveloped positive strand RNA virus that consists of several structural proteins including spike (S) protein, envelope (E) protein, membrane (M) protein and nucleocapsid (N) protein; and other non-structural proteins (NSPs). Spike proteins located on the surface of the virus, have a high affinity for binding to human receptor ACE2 (angiotensin-converting enzyme 2) within respiratory epithelial which serves as an entry mechanism for infection. As such, the S protein may be vital to blocking viral infection and vaccine development.