ATF2 anticorps
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- Antigène Voir toutes ATF2 Anticorps
- ATF2 (Activating Transcription Factor 2 (ATF2))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp ATF2 est non-conjugé
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Application
- Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS)
- Specificité
- This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene.
- Réactivité croisée (Details)
- Human. Predicted to react in mouse and rat.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogène
- Recombinant full-length human ATF2 protein
- Isotype
- IgG2b
- Top Product
- Discover our top product ATF2 Anticorps primaire
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- Indications d'application
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein), Western Blot (1-2 μg/mL),Optimal dilution for a specific application should be determined.
Positive_Control: HeLa or U87 cells.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Agent conservateur
- Azide free
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Date de péremption
- 24 months
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- Antigène
- ATF2 (Activating Transcription Factor 2 (ATF2))
- Autre désignation
- ATF2 (ATF2 Produits)
- Synonymes
- anticorps CRE-BP1, anticorps CREB2, anticorps HB16, anticorps TREB7, anticorps CG12850, anticorps CG3749, anticorps dATF-2, anticorps DmelCG30420, anticorps CG30420, anticorps CHN1, anticorps Atf-2, anticorps CRE-BP, anticorps Creb2, anticorps D130078H02Rik, anticorps D18875, anticorps Tg(Gzma-Klra1)7Wum, anticorps mXBP, anticorps atf2-A, anticorps atf2l, anticorps activating transcription factor 2, anticorps Activating transcription factor-2, anticorps activating transcription factor 2 S homeolog, anticorps ATF2, anticorps Atf-2, anticorps Atf2, anticorps atf2.S, anticorps atf2
- Sujet
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HB16, CREB2, TREB7, CREB-2, CRE-BP1,ATF2
Cellular localisation: Nucleus - Poids moléculaire
- 54.5kDa
- ID gène
- 1386, 592510
- UniProt
- P15336
- Pathways
- Signalisation MAPK, Signalisation RTK, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades
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