ERK2 anticorps

N° du produit ABIN7126836

Détail du produit anti-ERK2 anticorps

Antigène: ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ERK2 est non-conjugé

Application: ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Flow Cytometry (FACS), Coating (Coat)

Specificité: Mitogen-activated protein kinase (MAPK) signaling pathways involve two closely-related MAP kinases, known as extracellular-signal-related kinase 1 (ERK 1, p44) and 2 (ERK 2, p42). Growth factors, steroid hormones, G protein coupled receptor ligands and neurotransmitters can initiate MAPK signaling pathways. Activation of ERK 1 and ERK 2 requires phosphorylation by upstream kinases such as MAP kinase (MEK), MEK kinase and Raf-1. ERK 1 and ERK 2 phosphorylation can occur at specific tyrosine and threonine sites mapping within consensus motifs that include the threonine-glutamate-tyrosine motif. ERK activation leads to dimerization with other ERKs and subsequent localization to the nucleus. Active ERK dimers phosphorylate serine and threonine residues on nuclear proteins and influence a host of responses that include proliferation, differentiation, transcription regulation and development.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant full-length human MAPK1 protein

Isotype: IgG2b

Information d'application

Indications d'application:

Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (0.5-2 μg/million cells), Immunofluorescence (0.5-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: HeLa or U87 cells.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur ERK2

Antigène: ERK2 (MAPK1) (Mitogen-Activated Protein Kinase 1 (MAPK1))

Autre désignation: MAPK1 (MAPK1 Produits)

Synonymes: anticorps ERK-1, anticorps ERK1, anticorps ERT2, anticorps HS44KDAP, anticorps HUMKER1A, anticorps P44ERK1, anticorps P44MAPK, anticorps PRKM3, anticorps p44-ERK1, anticorps p44-MAPK, anticorps Erk-1, anticorps Erk1, anticorps Ert2, anticorps Esrk1, anticorps Mnk1, anticorps Mtap2k, anticorps Prkm3, anticorps p44, anticorps p44erk1, anticorps p44mapk, anticorps ERK, anticorps ERK2, anticorps ERT1, anticorps MAPK2, anticorps P42MAPK, anticorps PRKM1, anticorps PRKM2, anticorps p38, anticorps p40, anticorps p41, anticorps p41mapk, anticorps 9030612K14Rik, anticorps AA407128, anticorps AU018647, anticorps C78273, anticorps Erk2, anticorps Prkm1, anticorps p42mapk, anticorps zERK2, anticorps MAPK1, anticorps Xp42, anticorps erk, anticorps erk2, anticorps ert1, anticorps mapk, anticorps mapk1b, anticorps mapk2, anticorps mpk1, anticorps prkm1, anticorps prkm2, anticorps mapk1, anticorps mapk1a, anticorps xp42, anticorps ATMPK1, anticorps F14N23.9, anticorps F14N23_9, anticorps MITOGEN-ACTIVATED PROTEIN KINASE, anticorps mitogen-activated protein kinase 1, anticorps MNK1, anticorps ATMPK2, anticorps MITOGEN-ACTIVATED PROTEIN KINASE HOMOLOG 2, anticorps T30E16.13, anticorps T30E16_13, anticorps mitogen-activated protein kinase homolog 2, anticorps mitogen-activated protein kinase 3, anticorps mitogen-activated protein kinase 1, anticorps mitogen activated protein kinase 1, anticorps mitogen-activated protein kinase 1 L homeolog, anticorps mitogen-activated protein kinase 1 S homeolog, anticorps mitogen activated protein kinase 3, anticorps mitogen-activated protein kinase homolog 2, anticorps MAPK3, anticorps Mapk3, anticorps MAPK1, anticorps Mapk1, anticorps mapk1, anticorps mapk1.L, anticorps mapk1.S, anticorps PfMAP1, anticorps MPK1, anticorps PVX_084965, anticorps LOC9328617, anticorps Tsp_01601, anticorps MPK2

Sujet: Extracellular Signal Regulated Kinase 2, MAP kinase 1, MAP kinase 2, MAP kinase isoform p42, Mapk1, MAPK2, P38, P40, P41, p42-MAPK, PRKM1, PRKM2, protein kinase, mitogen-activated, 1 / 2, protein tyrosine kinase ERK2, ERT1,MAPK1 / ERK2 (Transcription Factor)
Cellular localisation: Nucleus.

Poids moléculaire: 41.3kDa

ID gène: 5594, 431850

UniProt: P28482

Pathways: Signalisation MAPK, Signalisation RTK, Apoptose, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Monocarboxylic Acid Catabolic Process, Autophagy, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, BCR Signaling, S100 Proteins