ZBED1 anticorps

N° du produit ABIN7127132

Détail du produit anti-ZBED1 anticorps

Antigène: ZBED1 (Zinc Finger, BED-Type Containing 1 (ZBED1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ZBED1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Specificité: ZBED1 (zinc finger BED domain-containing protein 1), also known as ALTE (Ac-like transposable element), DREF or TRAMP, is a 694 amino acid protein that localizes specifically to granular structures within the nucleus. Expressed ubiquitously at low levels and present at higher levels in heart, placenta, spleen and skeletal muscle, ZBED1 is thought to function as a transcription factor that regulates a number of ribosomal protein (RP) encoding genes, thereby playing a role in the cell cycle and in cell proliferation events. ZBED1 contains one BED-type zinc finger and binds specifically to 5'- TGTCG[CT]GA[CT]A-3' DNA regions found in RP promotors. Additionally, ZBED1 binds strongly to the promotor region of Histone H1 (a protein required for the condensation of nucleosomes into higher order structures), subsequently activating H1 transcription.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant full-length human ZBED1 protein

Isotype: IgG2a

Information d'application

Indications d'application:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Optimal dilution for a specific application should be determined.

Positive_Control: HeLa or HepG2 cells.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur ZBED1

Antigène: ZBED1 (Zinc Finger, BED-Type Containing 1 (ZBED1))

Autre désignation: ZBED1 (ZBED1 Produits)

Synonymes: anticorps ZBED1, anticorps ZBED1P, anticorps ALTE, anticorps DREF, anticorps TRAMP, anticorps hDREF, anticorps zinc finger BED-type containing 1, anticorps zinc finger, BED-type containing 1, anticorps ZBED1, anticorps zbed1

Sujet: Ac like transposable element, ALTE, BED type zinc finger domain containing protein 1, DNA replication related element binding factor, dREF homolog, hDREF, KIAA0785, Putative Ac-like transposable element, TRAMP, ZBED1, Zinc finger BED domain-containing protein 1,ZBED1 / DREF
Cellular localisation: Nucleus. In granular structures.

Poids moléculaire: 86kDa

ID gène: 9189, 131452

UniProt: O96006