ERCC6L anticorps

N° du produit ABIN7129394

Détail du produit anti-ERCC6L anticorps

Antigène: ERCC6L (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERCC6L est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: Antigen affinity purification

Immunogène: Fusion protein of Human ERCC6L

Isotype: IgG

Information d'application

Indications d'application: ELISA:1:2000-1:5000, IHC:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ERCC6L

Antigène: ERCC6L (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6-Like (ERCC6L))

Autre désignation: ERCC6L (ERCC6L Produits)

Synonymes: anticorps PICH, anticorps RAD26L, anticorps BC004701, anticorps D330021P09Rik, anticorps RGD1565734, anticorps fc22h03, anticorps si:ch211-278b8.3, anticorps wu:fc22h03, anticorps ERCC excision repair 6 like, spindle assembly checkpoint helicase, anticorps excision repair cross-complementing rodent repair deficiency complementation group 6 like, anticorps DNA excision repair protein ERCC-6-like, anticorps excision repair cross-complementation group 6-like, anticorps ERCC6L, anticorps Ercc6l, anticorps LOC100373376, anticorps LOC100494766, anticorps LOC100552957, anticorps LOC100560751, anticorps LOC100563247, anticorps ercc6l

Sujet:

Background: PICH (Plk1-interacting checkpoint helicase), also known as DNA excision repair protein ERCC-6-like (ERCC6L) or tumor antigen BJ-HCC-15, is a 1,250 amino acid protein belonging to the SNF2/RAD54 helicase family. PICH is a DNA helicase and an essential component of the spindle assembly checkpoint. During mitosis, PICH recruits MAD2 to kinetochores and also regulates the tension on centromic chromatin. PICH is concentrated in between the kinetochores in prometophase cells, while in metaphase it localizes to the thin threads composed of catenated centromeric DNA that stretch between sister kinetochores. PICH is phosphorylated by Plk, which prevents PICH from associating with chromosome arms and restricts the localization of PICH to the kinetochore-centromere region. PICH/Plk interaction is also required for correct Plk localization to the kinetochore. PICH contains one helicase ATP-binding domain, two TPR repeats and one helicase C-terminal domain.

Aliases: ATP dependent helicase ERCC6 like antibody, ATP-dependent helicase ERCC6-like antibody, DNA excision repair protein ERCC 6 like antibody, DNA excision repair protein ERCC-6-like antibody, ERC6L_HUMAN antibody, ERCC 6L antibody, Ercc6l antibody, Excision repair cross complementing rodent repair deficiency complementation group 6 like antibody, Excision repair protein ERCC6 like antibody, FLJ20105 antibody, MGC131695 antibody, PICH antibody, Plk1 interacting checkpoint helicase antibody, PLK1-interacting checkpoint helicase antibody, SNF2/RAD54 family protein antibody, Tumor antigen BJ HCC 15 antibody, Tumor antigen BJ-HCC-15 antibody

UniProt: Q2NKX8