FAM89B anticorps

N° du produit ABIN7129446

Détail du produit anti-FAM89B anticorps

Antigène: FAM89B (Family with Sequence Similarity 89, Member B (FAM89B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAM89B est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Réactivité croisée: Humain, Souris

Purification: Antigen affinity purification

Immunogène: Fusion protein of Human FAM89B

Isotype: IgG

Information d'application

Indications d'application: ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur FAM89B

Antigène: FAM89B (Family with Sequence Similarity 89, Member B (FAM89B))

Autre désignation: FAM89B (FAM89B Produits)

Synonymes: anticorps MTVR1, anticorps 1110021A21Rik, anticorps MMTV, anticorps Mtvr2, anticorps family with sequence similarity 89 member B, anticorps family with sequence similarity 89, member B, anticorps FAM89B, anticorps Fam89b

Sujet:

Background: Mtvr1 (mammary tumor virus receptor homolog 1), also known as FAM89B (family with sequence similarity 89, member B), is a 176 amino acid protein that exists as two alternatively spliced isoforms. Belonging to the FAM89 family, Mtvr1 is encoded by a gene that maps to human chromosome 11, which comprises approximately 4 % of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes.

Aliases: FAM89B antibody, Lrap25 antibody, Leucine repeat adapter protein 25 antibody

UniProt: Q8N5H3