LAT2 anticorps

N° du produit ABIN7130064

Détail du produit anti-LAT2 anticorps

Antigène: LAT2 (Linker For Activation of T Cells Family, Member 2 (LAT2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LAT2 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Réactivité croisée: Humain

Purification: Antigen affinity purification

Immunogène: Fusion protein of Human LAT2

Isotype: IgG

Information d'application

Indications d'application: ELISA:1:1000-1:5000, IHC:1:10-1:50,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur LAT2

Antigène: LAT2 (Linker For Activation of T Cells Family, Member 2 (LAT2))

Autre désignation: LAT2 (LAT2 Produits)

Synonymes: anticorps LAB, anticorps NTAL, anticorps WBSCR15, anticorps WBSCR5, anticorps WSCR5, anticorps LAT2, anticorps MGC139435, anticorps Ntal, anticorps Wbscr5, anticorps AW125574, anticorps Wbscr15, anticorps linker for activation of T-cells family member 2, anticorps linker for activation of T cells family, member 2, anticorps LAT2, anticorps Lat2

Sujet:

Background: This gene is one of the contiguous genes at 7q11.23 commonly deleted in Williams syndrome, a multisystem developmental disorder. This gene consists of at least 14 exons, and its alternative splicing generates 3 transcript variants, all encoding the same protein. Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.

Aliases: HSPC046 antibody, LAB antibody, LAT2 antibody, Linker for activation of B cells antibody, Linker for activation of B-cells antibody, Linker for activation of T cells family member 2 antibody, Linker for activation of T cells transmembrane adaptor 2 antibody, Linker for activation of T-cells family member 2 antibody, Membrane associated adapter molecule antibody, Membrane-associated adapter molecule antibody, Non T cell activation linker antibody, Non-T-cell activation linker antibody, NTAL_HUMAN antibody, WBSCR 5 antibody, Wbscr15 antibody, Williams Beuren syndrome chromosome region 15 antibody, Williams Beuren syndrome chromosome region 5 antibody, Williams-Beuren syndrome chromosomal region 15 protein antibody, Williams-Beuren syndrome chromosomal region 5 protein antibody, WSCR5 antibody

UniProt: Q9GZY6

Pathways: Fc-epsilon Receptor Signaling Pathway, BCR Signaling