MGEA5 anticorps

N° du produit ABIN7130225

Détail du produit anti-MGEA5 anticorps

Antigène: MGEA5 (Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MGEA5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Réactivité croisée: Humain, Souris, Rat

Purification: Antigen affinity purification

Immunogène: Fusion protein of Human MGEA5

Isotype: IgG

Information d'application

Indications d'application: ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MGEA5

Antigène: MGEA5 (Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5))

Autre désignation: MGEA5 (MGEA5 Produits)

Synonymes: anticorps MEA5, anticorps NCOAT, anticorps OGA, anticorps 2810009A20Rik, anticorps 4833427O07Rik, anticorps 5830447M11Rik, anticorps AA408215, anticorps Hy5, anticorps Ncoat, anticorps mKIAA0679, anticorps O-GLCNACASE, anticorps cytochrome c oxidase subunit VIc, anticorps meningioma expressed antigen 5 (hyaluronidase), anticorps COX6C, anticorps MGEA5, anticorps Mgea5

Sujet:

Background: The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT, which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications. Cleaves GlcNAc but not GalNAc from glycopeptides. Can use p-nitrophenyl-beta-GlcNAc as substrate but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc. Possesses hyaluronidase activity. Acetylates 'Lys-8' of histone H4 and 'Lys-14' of histone H3. Shows highest expression in the brain, placenta and pancreas.

Aliases: Beta-hexosaminidase antibody, Beta-N-acetylglucosaminidase antibody, Beta-N-acetylhexosaminidase antibody, Bifunctional protein NCOAT antibody, HEXC antibody, Hyaluronidase in meningioma antibody, KIAA0679 antibody, MEA5 antibody, Meningioma expressed antigen 5 antibody, Meningioma-expressed antigen 5 antibody, MGEA 5 antibody, Mgea5 antibody, N-acetyl-beta-D-glucosaminidase antibody, N-acetyl-beta-glucosaminidase antibody, NCOAT antibody, Nuclear cytoplasmic O GlcNAcase and acetyltransferase antibody, Nuclear cytoplasmic O-GlcNAcase and acetyltransferase antibody, OGA antibody, OGA_HUMAN antibody, Protein O-GlcNAcase antibody

UniProt: O60502

Pathways: Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process