TBC1D22A anticorps

N° du produit ABIN7131302

Détail du produit anti-TBC1D22A anticorps

Antigène: TBC1D22A (TBC1 Domain Family, Member 22A (TBC1D22A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TBC1D22A est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain, Souris

Purification: Antigen affinity purification

Immunogène: Fusion protein of Human TBC1D22A

Isotype: IgG

Information d'application

Indications d'application: ELISA:1:2000-1:5000, IHC:1:25-1:100,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TBC1D22A

Antigène: TBC1D22A (TBC1 Domain Family, Member 22A (TBC1D22A))

Autre désignation: TBC1D22A (TBC1D22A Produits)

Synonymes: anticorps C22orf4, anticorps HSC79E021, anticorps BC023106, anticorps D15Ertd781e, anticorps RGD1306588, anticorps TBC1 domain family member 22A, anticorps TBC1 domain family, member 22a, anticorps TBC1D22A, anticorps Tbc1d22a

Sujet:

Background: TBC1D22A (TBC1 domain family, member 22A), also known as C22orf4, is a 517 amino acid protein that contains one Rab-GAP TBC domain and is thought to function as a GTPase-activating protein for Rab family members. Multiple isoforms of TBC1D22A exist due to alternative splicing events. The gene encoding TBC1D22A maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.

Aliases: TBC1D22A antibody, C22orf4 antibody, TBC1 domain family member 22A antibody

UniProt: Q8WUA7