NAC1 anticorps
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- Antigène Voir toutes NAC1 (NACC1) Anticorps
- NAC1 (NACC1) (Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NAC1 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Réactivité croisée
- Humain
- Purification
- Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- Immunogène
- Peptide sequence around aa.519~523(A-G-P-S-A) derived from Human NAC1
- Isotype
- IgG
- Top Product
- Discover our top product NACC1 Anticorps primaire
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- Indications d'application
- WB:1:500-1:1000,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- NAC1 (NACC1) (Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1))
- Autre désignation
- NACC1 (NACC1 Produits)
- Synonymes
- anticorps BEND8, anticorps BTBD14B, anticorps BTBD30, anticorps NAC-1, anticorps NAC1, anticorps NACC1, anticorps 2010001H03Rik, anticorps 4930511N13Rik, anticorps Btbd14b, anticorps Nac1, anticorps Nac-1, anticorps nucleus accumbens associated 1, anticorps nucleus accumbens associated 1, BEN and BTB (POZ) domain containing, anticorps NACC1, anticorps Nacc1
- Sujet
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Background:
Functions as a transcriptional repressor. Seems to function as a transcriptional corepressor in neuronal cells through recruitment of HDAC3 and HDAC4. Contributes to tumor progression, and tumor cell proliferation and survival. This may be mediated at least in part through repressing transcriptional activity of GADD45GIP1. Required for recruiting the proteasome from the nucleus to the cytoplasm and dendritic spines. "A BTB/POZ protein, NAC-1, is related to tumor recurrence and is essential for tumor growth and survival."
Nakayama K., Nakayama N., Davidson B.,et al.
Proc. Natl. Acad. Sci. U.S.A. 103:18739-18744(2006) "NAC-1 controls cell growth and survival by repressing transcription of Gadd45GIP1, a candidate tumor suppressor."
Nakayama K., Nakayama N., Wang T.-L., Shih I.-M. Cancer Res. 67:8058-8064(2007)Aliases: BEND8 antibody; BTB Domain Containing 14B antibody; BTB/POZ domain-containing protein 14B antibody; btbd14b antibody; FLJ37383 antibody; NAC-1 antibody; NAC1 antibody; Nacc1 antibody; NACC1_HUMAN antibody; Nucleus accumbens-associated protein 1 antibody
- UniProt
- Q96RE7
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