GRIA2 anticorps (pSer880)

N° du produit ABIN7138720

Détail du produit anti-GRIA2 anticorps

Antigène: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Épitope: pSer880

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRIA2 est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée: Humain, Souris, Rat

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of serine 880 (I-E-S(p)-V-K) derived from Human Glutamate receptor 2.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:1000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur GRIA2

Antigène: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Autre désignation: GRIA2 (GRIA2 Produits)

Synonymes: anticorps GLUR2, anticorps GLURB, anticorps GluA2, anticorps GluR-K2, anticorps HBGR2, anticorps GluR-2, anticorps GluR-B, anticorps Glur-2, anticorps Glur2, anticorps GluR2, anticorps gluR-B, anticorps glur2a, anticorps gria2.1, anticorps zfGRIA2[a], anticorps glur2, anticorps glutamate ionotropic receptor AMPA type subunit 2, anticorps glutamate receptor, ionotropic, AMPA 2, anticorps glutamate receptor, ionotropic, AMPA2 (alpha 2), anticorps glutamate receptor, ionotropic, AMPA 2a, anticorps glutamate receptor, ionotropic, AMPA 2 S homeolog, anticorps GRIA2, anticorps Gria2, anticorps gria2a, anticorps gria2.S

Sujet:

Background:

Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.

Cull-Candy, S. et al. (2006) Curr. Opin. Neurobiol. 16, 288-297.
Hanley JG, et al. (2002) Neuron. 34(1): 53-67

Aliases: AMPA 2 antibody, AMPA selective glutamate receptor 2 antibody, AMPA-selective glutamate receptor 2 antibody, AMPA2 antibody, GluA2 antibody, GLUR 2 antibody, GLUR B antibody, GluR K2 antibody, GluR-2 antibody, GluR-B antibody, GluR-K2 antibody, GLUR2 antibody, GLURB antibody, Glutamate receptor 2 antibody, Glutamate receptor ionotropic AMPA 2 antibody, Glutamate receptor ionotropic antibody, Gria2 antibody, GRIA2_HUMAN antibody, HBGR2 antibody

UniProt: P42262

Pathways: Signalisation PI3K-Akt