BRAF anticorps (pThr753)
Aperçu rapide pour BRAF anticorps (pThr753) (ABIN7138881)
Antigène
Voir toutes BRAF AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pThr753
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Fonction
- Phospho-BRAF (Thr753) Antibody
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Réactivité croisée
- Souris, Rat
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Purification
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
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Immunogène
- Peptide sequence around phosphorylation site of threonine 753 (P-K-T(p)-P-L) derived from Human B-Raf.
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Isotype
- IgG
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))
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Autre désignation
- BRAF
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Sujet
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Background:
Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron.
Stephens R.M., Mol. Cell. Biol. 12:3733-3742(1992).
Albert S., Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
Scherer S.W., Science 300:767-772(2003)Aliases: FLJ95109 antibody, 94 kDa B raf protein antibody, B raf 1 antibody, B raf antibody, B Raf proto oncogene serine threonine protein kinase antibody, B Raf proto oncogene, serine/threonine kinase antibody, B RAF1 antibody, B-Raf proto-oncogene serine/threonine-protein kinase (p94) antibody, BRAF 1 antibody, BRAF antibody, BRAF_HUMAN antibody, BRAF1 antibody, cRmil antibody, MGC126806 antibody, MGC138284 antibody, Murine sarcoma viral (v-raf) oncogene homolog B1 antibody, Murine sarcoma viral v raf oncogene homolog B1 antibody, NS7 antibody, Oncogen BRAF antibody, oncogene BRAF1 antibody, p94 antibody, Proto-oncogene B-Raf antibody, Proto-oncogene c-Rmil antibody, RAFB 1 antibody, RAFB1 antibody, RMIL antibody, Serine/threonine-protein kinase B-raf antibody, v raf murine sarcoma viral oncogene homolog B antibody, v raf murine sarcoma viral oncogene homolog B1 antibody, v-Raf murine sarcoma viral oncogene homolog B1 antibody
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UniProt
- P15056
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Pathways
- Signalisation MAPK, Signalisation RTK, Neurotrophin Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Hepatitis C, Autophagy
Antigène
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