FCGR2B anticorps (pTyr292)

N° du produit ABIN7138969

Détail du produit anti-FCGR2B anticorps

Antigène: FCGR2B (Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B))

Épitope: pTyr292

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FCGR2B est non-conjugé

Application: Western Blotting (WB), ELISA

Réactivité croisée: Humain

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogène: Peptide sequence around phosphorylation site of tyrosine 292 (I-T-Y(p)-S-L) derived from Human CD32.

Isotype: IgG

Information d'application

Indications d'application: WB:1:500-1:1000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur FCGR2B

Antigène: FCGR2B (Fc Fragment of IgG, Low Affinity IIb, Receptor (CD32) (FCGR2B))

Autre désignation: FCGR2B (FCGR2B Produits)

Synonymes: anticorps CD32, anticorps CD32B, anticorps FCG2, anticorps FCGR2, anticorps IGFR2, anticorps FCGR2B, anticorps AI528646, anticorps F630109E10Rik, anticorps Fc[g]RII, anticorps FcgRII, anticorps Fcgr2, anticorps Fcgr2a, anticorps Fcr-2, anticorps Fcr-3, anticorps Ly-17, anticorps Ly-m20, anticorps LyM-1, anticorps Lym-1, anticorps FCRII, anticorps FcRII, anticorps Fc fragment of IgG receptor IIb, anticorps Fc fragment of IgG, low affinity IIb, receptor (CD32), anticorps Fc receptor, IgG, low affinity IIb, anticorps low affinity immunoglobulin gamma Fc region receptor II, anticorps FCGR2B, anticorps Fcgr2b, anticorps LOC100856270

Sujet:

Background:

Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.

Stuart S.G., EMBO J. 8:3657-3666(1989).
Brooks D.G., J. Exp. Med. 170:1369-1385(1989).
Engelhardt W., Eur. J. Immunol. 20:1367-1377(1990).

Aliases: CD32 antibody, CD32 antigen antibody, CD32B antibody, CDw32 antibody, Fc fragment of IgG, low affinity II, receptor for (CD32) antibody, Fc fragment of IgG, low affinity IIb, receptor antibody, Fc fragment of IgG, low affinity IIb, receptor (CD32) antibody, Fc fragment of IgG, low affinity IIb, receptor for (CD32) antibody, Fc fragment of IgG, low affinity IIb, receptor for antibody, Fc gamma receptor IIB antibody, Fc gamma RII antibody, Fc gamma RIIB antibody, Fc-gamma RII antibody, Fc-gamma RII-b antibody, Fc-gamma-RIIb antibody, FCG2 antibody, FCG2B_HUMAN antibody, Fcgr2 antibody, FCGR2B antibody, FCRII antibody, FcRII-b antibody, IGFR2 antibody, IgG Fc receptor II beta antibody, IgG Fc receptor II-b antibody, Low affinity immunoglobulin gamma Fc region receptor II antibody, Low affinity immunoglobulin gamma Fc region receptor II-b antibody, Ly-17 antibody, Lym 1 antibody, Lymphocyte antigen 17 antibody

UniProt: P31994

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, BCR Signaling