COL4a2 anticorps (AA 1493-1712) (HRP)

N° du produit ABIN7148246

Détail du produit anti-COL4a2 anticorps (HRP)

Antigène: COL4a2 (COL4A2) (Collagen, Type IV, alpha 2 (COL4A2))

Épitope: AA 1493-1712

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COL4a2 est conjugé à/à la HRP

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Collagen alpha-2(IV) chain protein (1493-1712AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur COL4a2

Antigène: COL4a2 (COL4A2) (Collagen, Type IV, alpha 2 (COL4A2))

Autre désignation: COL4A2 (COL4A2 Produits)

Synonymes: anticorps col4a2-a, anticorps zCanstatin, anticorps ICH, anticorps POREN2, anticorps Col4a-2, anticorps collagen, type IV, alpha 2 L homeolog, anticorps collagen type IV alpha 2 chain, anticorps collagen, type IV, alpha 2, anticorps col4a2.L, anticorps COL4A2, anticorps col4a2, anticorps Col4a2

Sujet:

Background: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a \\\'chicken-wire\\\' meshwork together with laminins, proteoglycans and entactin/nidogen. Canstatin, a cleavage product corresponding to the collagen alpha 2(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity. It inhibits proliferation and migration of endothelial cells, reduces mitochondrial membrane potential, and induces apoptosis. Specifically induces Fas-dependent apoptosis and activates procaspase-8 and -9 activity. Ligand for alphavbeta3 and alphavbeta5 integrins.

Aliases: Canstatin antibody, CO4A2_HUMAN antibody, COL4A 2 antibody, Col4a2 antibody, Collagen alpha 2(IV) chain antibody, Collagen, type IV, alpha 2 antibody

UniProt: P08572