Cytosolic Arginine Sensor For mTORC1 Subunit 2 (CASTOR2) (AA 82-329) anticorps (HRP)

N° du produit ABIN7149382

Détail du produit

Antigène: Cytosolic Arginine Sensor For mTORC1 Subunit 2 (CASTOR2)

Épitope: AA 82-329

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: HRP

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Cytosolic arginine sensor for mTORC1 subunit 2 protein (82-329AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détail du antigène

Antigène: Cytosolic Arginine Sensor For mTORC1 Subunit 2 (CASTOR2)

Autre désignation: CASTOR2

Sujet:

Background: Functions as a negative regulator of the TORC1 signaling pathway through the GATOR complex. As part of homodimers or heterodimers with CASTOR1, directly binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1. Does not directly bind arginine, but binding of arginine to CASTOR1 disrupts the interaction of CASTOR2-containing heterodimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway.

Aliases: CASTOR2 antibody, Cellular arginine sensor for mTORC1 protein 2 antibody, GATL2_HUMAN antibody, GATS-like protein 2 antibody, GATSL2 antibody

UniProt: A6NHX0