NFKBIE anticorps (pSer157)
-
- Antigène Voir toutes NFKBIE Anticorps
- NFKBIE (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, epsilon (NFKBIE))
-
Épitope
- pSer157
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp NFKBIE est non-conjugé
-
Application
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Homologie
- Human,Cow
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic phosphopeptide derived from human NFKBIE around the phosphorylation site of Ser157
- Isotype
- IgG
- Top Product
- Discover our top product NFKBIE Anticorps primaire
-
-
- Indications d'application
-
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
-
- Antigène
- NFKBIE (Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, epsilon (NFKBIE))
- Autre désignation
- Ikb epsilon (NFKBIE Produits)
- Synonymes
- anticorps NFKBIE, anticorps IKBE, anticorps Slc35b2, anticorps NFKB inhibitor epsilon, anticorps nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon, anticorps nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon, anticorps NFKBIE, anticorps Nfkbie
- Sujet
-
Synonyms: NFKBIE phospho S157, IKB epsilon Ser157, IKB epsilon S, p-IKB epsilon Ser157, p-IKB epsilon S157, I kappa B epsilon, IkappaBepsilon, IkB E, IKBE, IKB epsilon, MGC72568, NF kappa B inhibitor epsilon, NF kappa BIE, NFkappa BIE, NFkappaB inhibitor epsilon, NFKBIE, Nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor epsilon, OTTHUMP00000016522, Slc35b2, solute carrier family 35, member B2.
Background: NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T, R is an A or G purine, and Y is a C or T pyrimidine). For some genes, activation requires NFKB interaction with other transcription factors, such as STAT, AP1 (JUN), and NFAT.
- ID gène
- 4794
- Pathways
- Signalisation NF-kappaB, Maintenance of Protein Location
-