DNAJB6 anticorps (AA 208-326)

N° du produit ABIN7150528

Détail du produit anti-DNAJB6 anticorps

Antigène: DNAJB6 (DnaJ (Hsp40) Homolog, Subfamily B, Member 6 (DNAJB6))

Épitope: AA 208-326

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DNAJB6 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Réactivité croisée: Humain, Souris

Purification: >95%, Protein G purified

Immunogène: Recombinant Human DnaJ homolog subfamily B member 6 protein (208-326AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:2000-1:10000, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur DNAJB6

Antigène: DNAJB6 (DnaJ (Hsp40) Homolog, Subfamily B, Member 6 (DNAJB6))

Autre désignation: DNAJB6 (DNAJB6 Produits)

Synonymes: anticorps DJ4, anticorps DnaJ, anticorps HHDJ1, anticorps HSJ-2, anticorps HSJ2, anticorps LGMD1E, anticorps MRJ, anticorps MSJ-1, anticorps Mrj, anticorps mDj4, anticorps dnajb6, anticorps zgc:56709, anticorps hsj2, anticorps DnaJ heat shock protein family (Hsp40) member B6, anticorps DnaJ (Hsp40) homolog, subfamily B, member 6b, anticorps DnaJ heat shock protein family (Hsp40) member B6 S homeolog, anticorps DnaJ heat shock protein family (Hsp40) member B6 L homeolog, anticorps DNAJB6, anticorps Dnajb6, anticorps dnajb6b, anticorps dnajb6.S, anticorps dnajb6.L

Sujet:

Background: Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins. Isoform B but not isoform A inhibits huntingtin aggregation. Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Also reduces cellular toxicity and caspase-3 activity.

Aliases: DJ4 antibody, DnaJ antibody, DnaJ (Hsp40) homolog subfamily B member 6 antibody, DNAJ B6 antibody, DnaJ homolog subfamily B member 6 antibody, DnaJ like 2 protein antibody, DNAJB6 antibody, DNJB6_HUMAN antibody, Heat shock protein J2 antibody, HHDJ1 antibody, HSJ-2 antibody, HSJ2 antibody, LGMD1E antibody, MRJ antibody, MSJ-1 antibody, MSJ1 antibody

UniProt: O75190