TCEB2 anticorps (AA 1-118)

N° du produit ABIN7151593

Détail du produit anti-TCEB2 anticorps

Antigène: TCEB2 (Transcription Elongation Factor B (SIII), Polypeptide 2 (18kDa, Elongin B) (TCEB2))

Épitope: AA 1-118

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TCEB2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Elongin-B protein (1-118AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TCEB2

Antigène: TCEB2 (Transcription Elongation Factor B (SIII), Polypeptide 2 (18kDa, Elongin B) (TCEB2))

Autre désignation: ELOB (TCEB2 Produits)

Synonymes: anticorps 0610040H15Rik, anticorps cb162, anticorps wu:fb47e08, anticorps ELOB, anticorps SIII, anticorps elongin B, anticorps Elob, anticorps elob, anticorps ELOB

Sujet:

Background: SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex). The elongin BC complex seems to be involved as an adapter protein in the proteasomal degradation of target proteins via different E3 ubiquitin ligase complexes, including the von Hippel-Lindau ubiquitination complex CBC(VHL). By binding to BC-box motifs it seems to link target recruitment subunits, like VHL and members of the SOCS box family, to Cullin/RBX1 modules that activate E2 ubiquitination enzymes.

Aliases: EloB antibody, ELOB_HUMAN antibody, Elongin 18 kDa subunit antibody, Elongin B antibody, Elongin-B antibody, RNA polymerase II transcription factor SIII p18 subunit antibody, RNA polymerase II transcription factor SIII subunit B antibody, SIII antibody, SIII p18 antibody, TCEB 2 antibody, Tceb2 antibody, Transcription elongation factor B (SIII) polypeptide 2 antibody, Transcription elongation factor B polypeptide 2 antibody

UniProt: Q15370

Pathways: SARS-CoV-2 Protein Interactome