IGHA2 anticorps (AA 36-111) (Biotin)

N° du produit ABIN7378329

Détail du produit anti-IGHA2 anticorps (Biotin)

Antigène: IGHA2 (Immunoglobulin Heavy Constant alpha 2 (A2m Marker) (IGHA2))

Épitope: AA 36-111

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IGHA2 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Immunoglobulin heavy constant alpha 2 protein (36-111AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur IGHA2

Antigène: IGHA2 (Immunoglobulin Heavy Constant alpha 2 (A2m Marker) (IGHA2))

Autre désignation: IGHA2 (IGHA2 Produits)

Synonymes: anticorps immunoglobulin heavy constant alpha 2 (A2m marker), anticorps IGHA2

Sujet:

Background: Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268). Ig alpha is the major immunoglobulin class in body secretions (PubMed:2241915).

Aliases: IGHA2Immunoglobulin heavy constant alpha 2 antibody, Ig alpha-2 chain C region antibody, Ig alpha-2 chain C region BUT antibody, Ig alpha-2 chain C region LAN antibody

UniProt: P01877