IL1R1 anticorps (AA 18-320)

N° du produit ABIN7156743

Détail du produit anti-IL1R1 anticorps

Antigène: IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))

Épitope: AA 18-320

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL1R1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain, Souris

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Interleukin-1 receptor type 1 protein (18-320AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur IL1R1

Antigène: IL1R1 (Interleukin 1 Receptor, Type I (IL1R1))

Autre désignation: IL1R1 (IL1R1 Produits)

Synonymes: anticorps CD121A, anticorps D2S1473, anticorps IL-1R-alpha, anticorps IL1R, anticorps IL1RA, anticorps P80, anticorps CD121a, anticorps CD121b, anticorps IL-iR, anticorps Il1r-1, anticorps DER4, anticorps Fit-1, anticorps Ly84, anticorps ST2L, anticorps St2, anticorps St2-rs1, anticorps T1, anticorps T1/ST2, anticorps interleukin 1 receptor type 1, anticorps interleukin 1 receptor, type I, anticorps interleukin 1 receptor-like 1, anticorps IL1R1, anticorps Il1r1, anticorps Il1rl1

Sujet:

Background: Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the corecptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex.

Aliases: Antigen CD121a antibody, CD121 antigen-like family member A antibody, CD121a antibody, CD121a antigen antibody, D2S1473 antibody, IL 1 antibody, IL 1R 1 antibody, IL 1R alpha antibody, IL 1RT1 antibody, IL-1R-1 antibody, IL-1R-alpha antibody, IL-1RT-1 antibody, IL-1RT1 antibody, IL1 inhibitor antibody, IL1 Receptor I antibody, IL1R antibody, IL1R1 antibody, IL1R1_HUMAN antibody, IL1RA antibody, IL1RN antibody, IL1RT1 antibody, Interleukin 1 receptor alpha type 1 antibody, Interleukin 1 receptor antagonist protein (IRAP) antibody, Interleukin 1 receptor type I antibody, Interleukin receptor 1 antibody, Interleukin-1 receptor alpha antibody, Interleukin-1 receptor type 1 antibody, Interleukin-1 receptor type I antibody, p80 antibody

UniProt: P14778

Pathways: Signalisation NF-kappaB, Carbohydrate Homeostasis, Cancer Immune Checkpoints