SLC11A1 anticorps (AA 1-58) (Biotin)

N° du produit ABIN7161090

Détail du produit anti-SLC11A1 anticorps (Biotin)

Antigène: SLC11A1 (Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 1 (SLC11A1))

Épitope: AA 1-58

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC11A1 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Natural resistance-associated macrophage protein 1 protein (1-58AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SLC11A1

Antigène: SLC11A1 (Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 1 (SLC11A1))

Autre désignation: SLC11A1 (SLC11A1 Produits)

Synonymes: anticorps SLC11A1, anticorps NRAMP1, anticorps LSH, anticorps NRAMP, anticorps Bcg, anticorps Itg, anticorps Lsh, anticorps Nramp1, anticorps Ity, anticorps Nramp, anticorps ity, anticorps BCG, anticorps solute carrier family 11 member 1 L homeolog, anticorps solute carrier family 11 member 1, anticorps solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1, anticorps slc11a1.L, anticorps SLC11A1, anticorps Slc11a1

Sujet:

Background: Divalent transition metal (iron and manganese) transporter involved in iron metabolism and host resistance to certain pathogens. Macrophage-specific membrane transport function. Controls natural resistance to infection with intracellular parasites. Pathogen resistance involves sequestration of Fe(2+) and Mn(2+), cofactors of both prokaryotic and eukaryotic catalases and superoxide dismutases, not only to protect the macrophage against its own generation of reactive oxygen species, but to deny the cations to the pathogen for synthesis of its protective enzymes.

Aliases: LSH antibody, Natural resistance associated macrophage protein 1 antibody, Natural resistance-associated macrophage protein 1 antibody, NRAM1_HUMAN antibody, NRAMP 1 antibody, NRAMP antibody, PBC antibody, SLC11A1 antibody, Solute carrier family 11 (proton coupled divalent metal ion transporters) member 1 antibody, solute carrier family 11 (sodium/phosphate symporters) member 1 antibody, Solute carrier family 11 member 1 antibody

UniProt: P49279

Pathways: Transition Metal Ion Homeostasis, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus