NOTCH3 anticorps (AA 1301-1496)

N° du produit ABIN7161302

Cet anticorps Lapin Polyclonal détecte spécifiquement NOTCH3 dans ELISA et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour NOTCH3 anticorps (AA 1301-1496) (ABIN7161302)

Antigène: NOTCH3 (Notch 3 (NOTCH3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NOTCH3 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-NOTCH3 anticorps

Épitope: AA 1301-1496

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Neurogenic locus notch homolog protein 3 protein (1301-1496AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur NOTCH3

Antigène: NOTCH3 (Notch 3 (NOTCH3))

Autre désignation: NOTCH3

Sujet:

Background: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity).

Aliases: CADASIL antibody, CASIL antibody, NOTC3_HUMAN antibody, Notch 3 antibody, Notch 3 intracellular domain antibody, Notch homolog 3 antibody, Notch3 antibody

UniProt: Q9UM47

Pathways: Signalisation Notch