NUDT15 anticorps (AA 1-164) (FITC)
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- Antigène Voir toutes NUDT15 Anticorps
- NUDT15 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15))
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Épitope
- AA 1-164
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NUDT15 est conjugé à/à la FITC
- Application
- Veuillez nous consulter SVP
- Réactivité croisée
- Humain
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human Nucleotide triphosphate diphosphatase NUDT15 protein (1-164AA)
- Isotype
- IgG
- Top Product
- Discover our top product NUDT15 Anticorps primaire
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- NUDT15 (Nudix (Nucleoside Diphosphate Linked Moiety X)-Type Motif 15 (NUDT15))
- Autre désignation
- NUDT15 (NUDT15 Produits)
- Synonymes
- anticorps MTH2, anticorps RP11-90M2.1, anticorps 6530403O17, anticorps A730068G11Rik, anticorps nudix hydrolase 15, anticorps nudix (nucleoside diphosphate linked moiety X)-type motif 15, anticorps NUDT15, anticorps Nudt15
- Sujet
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Background: May catalyze the hydrolysis of nucleoside triphosphates including dGTP, dTTP, dCTP, their oxidized forms like 8-oxo-dGTP and the prodrug thiopurine derivatives 6-thio-dGTP and 6-thio-GTP (PubMed:26238318). Could also catalyze the hydrolysis of some nucleoside diphosphate derivatives (PubMed:22556419, PubMed:26238318). Hydrolyzes oxidized nucleosides triphosphates like 8-oxo-dGTP in vitro, but the specificity and efficiency towards these substrates are low. Therefore, the potential in vivo sanitizing role of this enzyme, that would consist in removing oxidatively damaged forms of nucleosides to prevent their incorporation into DNA, is unclear (PubMed:26238318, PubMed:22556419). Through the hydrolysis of thioguanosine triphosphates may participate in the catabolism of thiopurine drugs (PubMed:26238318, PubMed:25108385). May also have a role in DNA synthesis and cell cycle progression by stabilizing PCNA (PubMed:19419956).
Aliases: 8-dihydro-8-oxoguanine triphosphatase NUDT15 antibody, 8-oxo-dGTPase NUDT15 antibody, A730068G11Rik antibody, EC 3.1.6.- antibody, FLJ10956 antibody, MGC104352 antibody, MTH2 antibody, MutT homolog 2 antibody, Nucleoside diphosphate-linked moiety X motif 15 antibody, NUD15_HUMAN antibody, Nudix (nucleoside diphosphate linked moiety X)-type motif antibody, Nudix motif 15 antibody, NUDT15 antibody, OTTHUMP00000018389 antibody, Probable 7 antibody, Probable 7,8-dihydro-8-oxoguanine triphosphatase NUDT15 antibody, RP11-90M2.1 antibody
- UniProt
- Q9NV35
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