PLEKHO1 anticorps (AA 143-404) (FITC)

N° du produit ABIN7163660

Détail du produit anti-PLEKHO1 anticorps (FITC)

Antigène: PLEKHO1 (Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1))

Épitope: AA 143-404

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLEKHO1 est conjugé à/à la FITC

Application: Veuillez nous consulter SVP

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Pleckstrin homology domain-containing family O member 1 protein (143-404AA)

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PLEKHO1

Antigène: PLEKHO1 (Pleckstrin Homology Domain Containing, Family O Member 1 (PLEKHO1))

Autre désignation: PLEKHO1 (PLEKHO1 Produits)

Synonymes: anticorps CKIP-1, anticorps OC120, anticorps 2810052M02Rik, anticorps Ckip1, anticorps JZA-20, anticorps Jza2, anticorps RGD1311487, anticorps ckip-1, anticorps plekho1, anticorps si:dkey-200h23.2, anticorps pleckstrin homology domain containing O1, anticorps pleckstrin homology domain containing, family O member 1, anticorps pleckstrin homology domain containing, family O member 1a, anticorps PLEKHO1, anticorps Plekho1, anticorps plekho1a

Sujet:

Background: Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2). Appears to target ATM to the plasma membrane. Appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival. Also implicated in PI3K-regulated muscle differentiation, the regulation of AP-1 activity (plasma membrane bound AP-1 regulator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF. When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation.

Aliases: C-Jun-binding protein antibody, Casein kinase 2-interacting protein 1 antibody, CK2 interacting protein 1 antibody, CK2 interacting protein 1 HQ0024c protein antibody, CK2-interacting protein 1 antibody, CKIP 1 antibody, CKIP-1 antibody, CKIP1 antibody, JBP antibody, OC120 antibody, Osteoclast maturation associated gene 120 protein antibody, Osteoclast maturation-associated gene 120 protein antibody, PH domain-containing family O member 1 antibody, PKHO1_HUMAN antibody, Pleckstrin homology domain containing family O member 1 antibody, Pleckstrin homology domain-containing family O member 1 antibody, PLEKHO1 antibody

UniProt: Q53GL0