CBFA2T2 anticorps (AA 325-604)
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- Antigène Voir toutes CBFA2T2 Anticorps
- CBFA2T2 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2))
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Épitope
- AA 325-604
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CBFA2T2 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Réactivité croisée
- Humain
- Purification
- Antigen Affinity Purified
- Immunogène
- Recombinant Human Protein CBFA2T2 protein (325-604AA)
- Isotype
- IgG
- Top Product
- Discover our top product CBFA2T2 Anticorps primaire
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- Indications d'application
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- CBFA2T2 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 2 (CBFA2T2))
- Autre désignation
- CBFA2T2 (CBFA2T2 Produits)
- Synonymes
- anticorps MTGR1, anticorps A430091M07, anticorps C330013D05Rik, anticorps Cbfa2t2h, anticorps EHT, anticorps ZMYND3, anticorps p85, anticorps XETOR, anticorps cbfa2t2-a, anticorps CBFA2/RUNX1 translocation partner 2, anticorps core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human), anticorps CBFA2/RUNX1 translocation partner 2 L homeolog, anticorps Cbfa2t2, anticorps CBFA2T2, anticorps cbfa2t2.L
- Sujet
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Background: Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes (PubMed:12559562, PubMed:15203199). Can repress the expression of MMP7 in a ZBTB33-dependent manner (PubMed:23251453). May function as a complex with the chimeric protein RUNX1/AML1-CBFA2T1/MTG8 which is produced in acute myeloid leukemia with the chromosomal translocation t(8,21). May thus be involved in the repression of AML1-dependent transcription and the induction of G-CSF/CSF3-dependent cell growth. May be a tumor suppressor gene candidate involved in myeloid tumors with the deletion of the 20q11 region.
Aliases: AML1 MTG8 antibody, cbfa2t2 antibody, Core binding factor runt domain alpha subunit 2 translocated to 2 antibody, core-binding factor, runt domain, alpha subunit 2 antibody, DKFZp313F2116 antibody, EHT antibody, ETO homolog on chromosome 20 antibody, ETO homologous on chromosome 20 antibody, MTG 8 like protein antibody, MTG 8 related protein 1 antibody, MTG8 like protein antibody, MTG8 related protein 1 antibody, MTG8-like protein antibody, MTG8-related protein 1 antibody, MTG8R_HUMAN antibody, MTGR 1 antibody, Myeloid translocation gene related protein 1 antibody, Myeloid translocation related protein 1 antibody, Myeloid translocation-related protein 1 antibody, p85 antibody, Protein CBFA2T2 antibody, ZMYND 3 antibody, ZMYND3 antibody
- UniProt
- O43439
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