STAM2 anticorps (AA 376-525)

N° du produit ABIN7169694

Détail du produit anti-STAM2 anticorps

Antigène: STAM2 (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2))

Épitope: AA 376-525

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STAM2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Signal transducing adapter molecule 2 protein (376-525AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur STAM2

Antigène: STAM2 (Signal Transducing Adaptor Molecule (SH3 Domain and ITAM Motif) 2 (STAM2))

Autre désignation: STAM2 (STAM2 Produits)

Synonymes: anticorps Hbp, anticorps STAM2A, anticorps STAM2B, anticorps 1200004O12Rik, anticorps 5730456G07Rik, anticorps BB145015, anticorps stam2, anticorps MGC52950, anticorps zgc:103628, anticorps signal transducing adaptor molecule 2, anticorps signal transducing adaptor molecule (SH3 domain and ITAM motif) 2, anticorps signal transducing adaptor molecule 2 S homeolog, anticorps STAM2, anticorps Stam2, anticorps stam2.S, anticorps stam2

Sujet:

Background: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity).

Aliases: DKFZp564C047 antibody, Hbp antibody, Hrs-binding protein antibody, HSE1 homolog antibody, Signal transducing adapter molecule 2 antibody, Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 antibody, Signal transducing adaptor molecule 2A antibody, Signal transducing adaptor molecule 2B antibody, Signal transducing adaptor molecule antibody, STAM like protein containing SH3 and ITAM domains 2 antibody, STAM-2 antibody, Stam2 antibody, STAM2_HUMAN antibody, STAM2A antibody, STAM2B antibody

UniProt: O75886

Pathways: EGFR Signaling Pathway, EGFR Downregulation