RAD9A anticorps (pSer336) (FITC)

N° du produit ABIN712788

Cet anticorps anti-RAD9A est un anticorps Lapin Polyclonal détectant RAD9A dans IF (p) et IF (cc). Adapté pour Humain.

Aperçu rapide pour RAD9A anticorps (pSer336) (FITC) (ABIN712788)

Antigène: RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD9A est conjugé à/à la FITC

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Détail du produit anti-RAD9A anticorps (FITC)

Épitope: pSer336

Homologie: Human

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human RAD9 around the phosphorylation site of Ser336 [PH(p-S)EE]

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C/-80 °C

Stockage commentaire: Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles

Date de péremption: 12 months

Détails sur RAD9A

Antigène: RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))

Autre désignation: RAD9

Sujet:

This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein is found to possess 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Use of alternative polyA sites has been noted for this gene. [provided by RefSeq].

Subcellular location: Nucleus

Synonyms: RAD9Aphospho S336, Cell cycle checkpoint control protein, Cell cycle checkpoint control protein RAD9A, DNA repair exonuclease rad9 homolog A, hRAD 9, hRAD9, Rad 9, RAD 9A, RAD9 S pombe homolog, RAD9 homolog A, RAD9 homolog, RAD9A, RAD9A_HUMAN.

ID gène: 5883

Pathways: Positive Regulation of Response to DNA Damage Stimulus