SORL1 anticorps (AA 525-744) (Biotin)

N° du produit ABIN7170340

Détail du produit anti-SORL1 anticorps (Biotin)

Antigène: SORL1 (Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1))

Épitope: AA 525-744

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SORL1 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Sortilin-related receptor protein (525-744AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SORL1

Antigène: SORL1 (Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1))

Autre désignation: SORL1 (SORL1 Produits)

Synonymes: anticorps SORL1, anticorps C11orf32, anticorps LR11, anticorps LRP9, anticorps SORLA, anticorps SorLA-1, anticorps gp250, anticorps SorLA, anticorps 2900010L19Rik, anticorps AI596264, anticorps AW261561, anticorps mSorLA, anticorps Lr11, anticorps RGD619914, anticorps sortilin related receptor 1, anticorps sortilin-related receptor, anticorps sortilin-related receptor, L(DLR class) A repeats containing, anticorps sortilin-related receptor, L(DLR class) A repeats-containing, anticorps sortilin-related receptor, LDLR class A repeats-containing, anticorps sorl1, anticorps LOC582560, anticorps SORL1, anticorps Sorl1

Sujet:

Background: Likely to be a multifunctional endocytic receptor, that may be implicated in the uptake of lipoproteins and of proteases. Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. Binds the receptor-associated protein (RAP). Could play a role in cell-cell interaction. Involved in APP trafficking to and from the Golgi apparatus. It probably acts as a sorting receptor that protects APP from trafficking to late endosome and from processing into amyloid beta, thereby reducing the burden of amyloidogenic peptide formation. Involved in the regulation of smooth muscle cells migration, probably through PLAUR binding and decreased internalization.

Aliases: C11orf32 antibody, FLJ21930 antibody, FLJ39258 antibody, gp250 antibody, LDLR relative with 11 ligand binding repeats antibody, LDLR relative with 11 ligand-binding repeats antibody, Low density lipoprotein receptor relative with 11 ligand binding repeats antibody, Low-density lipoprotein receptor relative with 11 ligand-binding repeats antibody, LR 11 antibody, LR11 antibody, LRP 9 antibody, LRP9 antibody, Mosaic protein LR11 antibody, SORL 1 antibody, SORL_HUMAN antibody, SORL1 antibody, SorLA 1 antibody, SorLA antibody, SorLA-1 antibody, Sortilin related receptor antibody, Sortilin related receptor L(DLR class) A repeats containing antibody, Sortilin-related receptor antibody, Sorting protein related receptor containing LDLR class A repeats antibody, Sorting protein-related receptor containing LDLR class A repeats antibody

UniProt: Q92673

Pathways: Smooth Muscle Cell Migration