U2AF2 anticorps (AA 124-246) (Biotin)

N° du produit ABIN7170634

Détail du produit anti-U2AF2 anticorps (Biotin)

Antigène: U2AF2 (U2AF59) (U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59))

Épitope: AA 124-246

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp U2AF2 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Splicing factor U2AF 65 kDa subunit protein (124-246AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur U2AF2

Antigène: U2AF2 (U2AF59) (U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59))

Autre désignation: U2AF2 (U2AF59 Produits)

Synonymes: anticorps U2AF65, anticorps 65kDa, anticorps u2af65, anticorps U2AF2, anticorps DDBDRAFT_0186947, anticorps DDBDRAFT_0233353, anticorps DDB_0186947, anticorps DDB_0233353, anticorps zgc:110115, anticorps U2 small nuclear RNA auxiliary factor 2, anticorps U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2, anticorps U2 small nuclear RNA auxiliary factor 2 S homeolog, anticorps RNA recognition motif-containing protein RRM, anticorps Splicing factor U2AF 65 kDa subunit, anticorps U2 small nuclear RNA auxiliary factor 2a, anticorps U2AF2, anticorps U2af2, anticorps u2af2.S, anticorps u2af2, anticorps u2af2a

Sujet:

Background: Necessary for the splicing of pre-mRNA. By recruiting PRPF19 and the PRP19C/Prp19 complex/NTC/Nineteen complex to the RNA polymerase II C-terminal domain (CTD), and thereby pre-mRNA, may couple transcription to splicing (PubMed:21536736). Induces cardiac troponin-T (TNNT2) pre-mRNA exon inclusion in muscle. Regulates the TNNT2 exon 5 inclusion through competition with MBNL1. Binds preferentially to a single-stranded structure within the polypyrimidine tract of TNNT2 intron 4 during spliceosome assembly. Required for the export of mRNA out of the nucleus, even if the mRNA is encoded by an intron-less gene. Represses the splicing of MAPT/Tau exon 10.

Aliases: hU2AF(65) antibody, hU2AF65 antibody, Splicing factor U2AF 65 kDa subunit antibody, U2 (RNU2) small nuclear RNA auxiliary factor 2 antibody, U2 auxiliary factor 65 kDa subunit antibody, U2 small nuclear ribonucleoprotein auxiliary factor (65kD) antibody, U2 small nuclear RNA auxiliary factor 2 antibody, U2 snRNP auxiliary factor large subunit antibody, U2af2 antibody, U2AF2_HUMAN antibody, U2AF65 antibody

UniProt: P26368