SMARCC1 anticorps (AA 80-320)

N° du produit ABIN7171052

Détail du produit anti-SMARCC1 anticorps

Antigène: SMARCC1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily C, Member 1 (SMARCC1))

Épitope: AA 80-320

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMARCC1 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human SWI/SNF complex subunit SMARCC1 protein (80-320AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SMARCC1

Antigène: SMARCC1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily C, Member 1 (SMARCC1))

Autre désignation: SMARCC1 (SMARCC1 Produits)

Synonymes: anticorps smarcc1, anticorps MGC53976, anticorps BAF155, anticorps CRACC1, anticorps Rsc8, anticorps SRG3, anticorps SWI3, anticorps AI115498, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 L homeolog, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1a, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1, anticorps smarcc1.L, anticorps smarcc1a, anticorps SMARCC1, anticorps Smarcc1

Sujet:

Background: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). May stimulate the ATPase activity of the catalytic subunit of the complex. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).

Aliases: AI115498 antibody, BAF 155 antibody, BAF155 antibody, BRG 1 associated factor 155 antibody, BRG1 associated factor 155 antibody, BRG1-associated factor 155 antibody, Chromatin remodeling complex BAF155 subunit antibody, CRACC 1 antibody, CRACC1 antibody, Mammalian chromatin remodeling complex BRG 1 associated factor 155 antibody, Mammalian chromatin remodeling complex BRG1 associated factor 155 antibody, Rsc 8 antibody, Rsc8 antibody, SMARC C1 antibody, SMARCC 1 antibody, SMARCC1 antibody, SMRC1_HUMAN antibody, SRG 3 antibody, SRG3 antibody, SWI 3 antibody, SWI/SNF complex 155 kDa subunit antibody, SWI/SNF complex subunit SMARCC1 antibody, SWI/SNF related matrix associated actin dependent regulator of chromatin c1 antibody, SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily c member 1 antibody, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1 antibody, SWI3 antibody

UniProt: Q92922

Pathways: Chromatin Binding