ERCC2 anticorps (AA 1-300)

N° du produit ABIN7171955

Détail du produit anti-ERCC2 anticorps

Antigène: ERCC2 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 (ERCC2))

Épitope: AA 1-300

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERCC2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human TFIIH basal transcription factor complex helicase XPD subunit protein (1-300AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ERCC2

Antigène: ERCC2 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 (ERCC2))

Autre désignation: ERCC2 (ERCC2 Produits)

Synonymes: anticorps COFS2, anticorps EM9, anticorps TTD, anticorps XPD, anticorps AA407812, anticorps AU020867, anticorps AW240756, anticorps CXPD, anticorps Ercc-2, anticorps MGC89573, anticorps CG9433, anticorps DhR3, anticorps DhXPD, anticorps DmXPD, anticorps Dmel\\CG9433, anticorps ERCC2, anticorps XPD/ERCC2, anticorps l(2)SH2 2137, anticorps l(2)SH2137, anticorps xpd, anticorps zgc:56365, anticorps ERCC excision repair 2, TFIIH core complex helicase subunit, anticorps excision repair cross-complementing rodent repair deficiency, complementation group 2, anticorps excision repair cross-complementation group 2, anticorps Xeroderma pigmentosum D, anticorps ERCC2, anticorps Ercc2, anticorps ercc2, anticorps Xpd

Sujet:

Background: ATP-dependent 5\\\'-3\\\' DNA helicase, component of the core-TFIIH basal transcription factor. Involved in nucleotide excision repair (NER) of DNA by opening DNA around the damage, and in RNA transcription by RNA polymerase II by anchoring the CDK-activating kinase (CAK) complex, composed of CDK7, cyclin H and MAT1, to the core-TFIIH complex. Involved in the regulation of vitamin-D receptor activity. As part of the mitotic spindle-associated MMXD complex it plays a role in chromosome segregation. Might have a role in aging process and could play a causative role in the generation of skin cancers.

Aliases: TFIIH 80 kDa subunit antibody, Basic transcription factor 2 80 kDa subunit antibody, BTF2 p80 antibody, COFS 2 antibody, COFS2 antibody, CXPD antibody, DNA excision repair protein ERCC 2 antibody, DNA excision repair protein ERCC-2 antibody, DNA repair protein complementing XP D cells antibody, DNA repair protein complementing XP-D cells antibody, EM9 antibody, ERCC 2 antibody, ERCC2 antibody, ERCC2_HUMAN antibody, Excision repair 2 antibody, Excision repair cross complementing rodent repair deficiency complementation antibody, Excision repair cross complementing rodent repair deficiency, complementation group 2 antibody, MAG antibody, MGC102762 antibody, MGC126218 antibody, MGC126219 antibody, OTTHUMP00000045860 antibody, OTTHUMP00000045861 antibody, OTTHUMP00000045862 antibody, OTTHUMP00000045863 antibody, TFIIH 80 kDa subunit antibody, TFIIH basal transcription factor complex 80 kDa subunit antibody, TFIIH Basal Transcription Factor Complex Helicase Subunit antibody, TFIIH basal transcription factor complex helicase XPD subunit antibody, TFIIH basal transcription factor complex p80 subunit antibody, TFIIH p80 antibody, TTD antibody, Xeroderma pigmentosum complementary group D antibody, Xeroderma pigmentosum group D complementing protein antibody, Xeroderma pigmentosum group D-complementing protein antibody, XPD antibody, XPDC antibody

UniProt: P18074

Pathways: Réparation de l'ADN