TRAF3 anticorps (AA 1-40)

N° du produit ABIN7172236

Cet anticorps anti-TRAF3 est un anticorps Lapin Polyclonal détectant TRAF3 dans WB, ELISA et IF. Adapté pour Humain.

Aperçu rapide pour TRAF3 anticorps (AA 1-40) (ABIN7172236)

Antigène: TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRAF3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Détail du produit anti-TRAF3 anticorps

Épitope: AA 1-40

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human TNF receptor-associated factor 3 protein (1-40AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:200-1:2000, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TRAF3

Antigène: TRAF3 (TNF Receptor-Associated Factor 3 (TRAF3))

Autre désignation: TRAF3

Sujet:

Background: Regulates pathways leading to the activation of NF-kappa-B and MAP kinases, and plays a central role in the regulation of B-cell survival. Part of signaling pathways leading to the production of cytokines and interferon. Required for normal antibody isotype switching from IgM to IgG. Plays a role T-cell dependent immune responses. Plays a role in the regulation of antiviral responses. Is an essential constituent of several E3 ubiquitin-protein ligase complexes. May have E3 ubiquitin-protein ligase activity and promote \\\'Lys-63\\\'-linked ubiquitination of target proteins. Inhibits activation of NF-kappa-B in response to LTBR stimulation. Inhibits TRAF2-mediated activation of NF-kappa-B. Down-regulates proteolytic processing of NFKB2, and thereby inhibits non-canonical activation of NF-kappa-B. Promotes ubiquitination and proteasomal degradation of MAP3K14.

Aliases: CAP 1 antibody, CAP-1 antibody, CAP1 antibody, CD40 associated protein 1 antibody, CD40 binding protein antibody, CD40 bp antibody, CD40 receptor associated factor 1 antibody, CD40 receptor-associated factor 1 antibody, CD40-binding protein antibody, CD40BP antibody, CRAF 1 antibody, CRAF1 antibody, IIAE5 antibody, LAP 1 antibody, LAP1 antibody, LMP1 associated protein antibody, LMP1-associated protein 1 antibody, MIPT3 antibody, TNF receptor associated factor 3 antibody, TNF receptor-associated factor 3 antibody, TRAF 3 antibody, Traf3 antibody, TRAF3_HUMAN antibody

UniProt: Q13114

Pathways: Signalisation NF-kappaB, Apoptose, Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades