TEAD1 anticorps (AA 135-215)

N° du produit ABIN7172758

Détail du produit anti-TEAD1 anticorps

Antigène: TEAD1 (TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1))

Épitope: AA 135-215

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TEAD1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Transcriptional enhancer factor TEF-1 protein (135-215AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur TEAD1

Antigène: TEAD1 (TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor) (TEAD1))

Autre désignation: TEAD1 (TEAD1 Produits)

Synonymes: anticorps tead1, anticorps zgc:63696, anticorps TEAD1, anticorps xtead1, anticorps 2610024B07Rik, anticorps B230114H05Rik, anticorps Gtrgeo5, anticorps TEAD-1, anticorps TEF-1, anticorps Tcf13, anticorps mTEF-1, anticorps AA, anticorps NTEF-1, anticorps REF1, anticorps TCF-13, anticorps TCF13, anticorps XNTEF-1, anticorps xlNTEF-1, anticorps TEA domain family member 1a, anticorps TEA domain transcription factor 1, anticorps TEA domain family member 1 (SV40 transcriptional enhancer factor), anticorps TEA domain family member 1, anticorps TEA domain family member 1 (SV40 transcriptional enhancer factor) S homeolog, anticorps TEA domain family member 1b, anticorps tead1a, anticorps TEAD1, anticorps tead1, anticorps Tead1, anticorps tead1.S, anticorps tead1b

Sujet:

Background: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and cooperatively to the SPH and GT-IIC \\\'enhansons\\\' (5\\\'-GTGGAATGT-3\\\') and activates transcription in vivo in a cell-specific manner. The activation function appears to be mediated by a limiting cell-specific transcriptional intermediary factor (TIF). Involved in cardiac development. Binds to the M-CAT motif.

Aliases: AA antibody, Atrophia areata peripapillary chorioretinal degeneration antibody, NTEF 1 antibody, NTEF-1 antibody, NTEF1 antibody, Protein GT IIC antibody, Protein GT-IIC antibody, REF 1 antibody, REF1 antibody, SV40 transcriptional enhancer factor antibody, TCF 13 antibody, TCF-13 antibody, TCF13 antibody, TEA domain family member antibody, TEA domain family member 1 (SV40 transcriptional enhancer factor) antibody, TEA domain family member 1 antibody, TEAD 1 antibody, TEAD 1 protein antibody, TEAD-1 antibody, TEAD1 antibody, TEAD1 protein antibody, TEAD1_HUMAN antibody, TEF 1 antibody, TEF1 antibody, Transcription factor 13 (SV40 transcriptional enhancer factor) antibody, Transcription factor 13 antibody, Transcriptional enhancer factor 1 antibody, Transcriptional enhancer factor TEF-1 antibody, Transcriptional enhancer factor TEF1 antibody

UniProt: P28347

Pathways: Regulation of Lipid Metabolism by PPARalpha